LIVER СHANGES AND ITS ROLE IN PREDICTING PREECLAMPSIA

Abstract

This article considers the etiopathogenetic and clinical significance of increased intra-abdominal pressure, intra-abdominal hypertension (IAH) and cardiovascular maladaptation (CVD) in the development of preeclampsia. None of the existing theories fully explains the pathogenetic mechanisms leading to the development of preeclampsia. Preeclampsia is characterized by intra-abdominal compression of the kidneys, mesenteric and pelvic vessels, venous hyperemia and, as a result, ischemia of the kidneys, uterine-fetal-placental complex, liver, and pathological activation of the renin-angiotensin system. This article provides an insight into the role of intra-abdominal hypertension in the development of a complex of hemodynamic, respiratory and renal disorders that ultimately lead to preeclampsia and multiple organ failure in pregnant women. The article discusses the Doppler signs of intra-abdominal hypertension in the prognosis of preeclampsia, characterizes the qualitative and quantitative indicators of the Doppler wave patterns of the renal and hepatic vessels.