ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES
type: channel
description: ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES - is the official publication of the Science, Medicine and Natural History Society. It considers the following types of original material for review and publication: research articles, review articles, letters to the editor, briefs, case reports, book reviews, technology reports, and article reviews. Each issue covers topics of interest to a broad readership, industry, clinicians, academia, and government. A magazine for anyone interested in science. We are pleased to offer all interested authors the opportunity to publish in the pages of the journal. The magazine is intended for professional doctors and pharmacologists, researchers and university teachers. Articles of a problematic and scientific-practical nature are published in the magazine.
publisher: Innovative World LLC
language: en
publication name: ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES
issn: 3030-3591
items: ОЦЕНКА КАЧЕСТВА СКОРОПОРТЯЩИХСЯ ПИЩЕВЫХ ПРОДУКТОВ
items: Охрана труда в сельском хозяйстве. Влияние токсичных химических веществ на здоровье человека и профилактические меры
items: Постменопаузальный генитоуринарный синдром: клинико-патогенетические аспекты, диагностика и современные подходы к терапии
items: Myocardial infarction: etiology, clinical characteristics, myocardial biomarkers, pathophysiological and anatomical features based on clinical research and statistical analysis
items: Miokard infarktning ilk va kechki bosqichlaridagi gistologik o‘zgarishlar. Hujayra darajasidagi aniqlovchi omillar
items: Clinical effectiveness of modern endodontic diagnostic methods: a theoretical and evidence-based analysis
items: Conservative and surgical treatment approaches for periodontitis with emphasis on apical root resection: an evidence-based theoretical and statistical analysis
items: STENORKARDIYA KASALLIGI, UNING DIAGNOSTIKASI HAMDA TERAPIYASI
items: PARKINSON KASALLIGI ETIOLOGIYASI, PATOGENEZI HAMDA DAVOLASH USULLARI
items: Ambulatoriya sharoitida homilador ayollarda temir tanqisligi anemiyasini davolashni takomillashtirish
items: Temir tanqisligi anemiyasidan aziyat chekuvchi xomilador ayollarda preeklampsiya profilaktikasining samaradorligi
items: Особенности ранней диагностики и факторы риска осложнения муковисцидоза у детей раннего возраста
items: Возможности ультразвукового исследования в выявлении смещения суставного диска при дисфункции височно-нижнечелюстного сустава
items: CHRONIC GANGRENOUS PULPITIS: ETIOLOGY, CLINICOPATHOLOGICAL CHARACTERISTICS AND PATHOGENESIS
items: Maktab yoshdagi bolalarda karies rivojlanishining asosiy xavf omillari: etiologiyasi, klinikasi va profilaktik chora-tadbirlari
items: THE ROLE OF MITOCHONDRIAL DYSFUNCTION IN HUMAN DISEASES
items: TEACHING MEDICAL STUDENTS ABOUT MORPHOLOGICAL CHANGES IN DIFFERENT PARENCHYMATOUS ORGANS
items: IMPROVING MEDICAL STUDENTS' CRITICAL THINKING IN PATIENT DIAGNOSIS
items: Embrional rivojlanish davrlari va uning umumiy tavsifi: urug‘lanish, zigota, maydalanish, blastula, gastrulyatsiya, gistogenez, organogenez
items: EARLY IDENTIFICATION OF OVARIAN FUNCTIONAL DECLINE AND CONTEMPORARY APPROACHES TO CLINICAL MANAGEMENT
items: GAYMORID: KELIB CHIQISH SABABLARI, BELGILARI VA DAVOLASH USULLARI
items: ХАВФ ОМИЛЛАРИНИ ТАРҚАЛИШИНИ ЮРАК-ҚОН ТОМИР КАСАЛЛИКЛАРИ УЧУН ТАХЛИЛ ҚИЛИШ
items: Kuyish jarohatlarida AST va ALT ko‘rsatkichlarining o‘zgarishi: RSHTYoIM BF kuzatuvlari asosida
items: HAMSHIRALIK XIZMATIDA EMPATIYA VA KOMMUNIKATIV KO'NIKMALARNING AHAMIYATI
items: Jamiyatda daltanizm: muammolar va yechimlar
items: Новые стратегии борьбы с антибиотикорезистентностью: современное состояние и перспективные направления
items: ГАСТРИТ: ЭТИОЛОГИЯ, ПАТОГЕНЕЗ, КЛИНИЧЕСКИЕ ПРОЯВЛЕНИЯ И СОВРЕМЕННЫЕ ПОДХОДЫ К ЛЕЧЕНИЮ
items: METABOLIK SINDROM: PATOGENEZ, KLINIK AHAMIYATI VA PROFILAKTIK YONDASHUVLAR
items: GASTRIT: ETIOLOGIYASI, PATOGENEZI, KLINIK KO‘RINISHLARI VA DAVOLASHNING ZAMONAVIY YONDASHUVLARI
items: МЕТАБОЛИЧЕСКИЙ СИНДРОМ: ПАТОГЕНЕЗ, КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ И ПРОФИЛАКТИЧЕСКИЕ ПОДХОДЫ

ОЦЕНКА КАЧЕСТВА СКОРОПОРТЯЩИХСЯ ПИЩЕВЫХ ПРОДУКТОВ
type: item
description: В обзорной статье рассматриваются современные подходы к оценке качества скоропортящихся пищевых продуктов с позиций гигиены питания и пищевой безопасности. Проанализированы основные физико-химические, микробиологические и органолептические показатели, используемые для определения свежести и безопасности скоропортящихся продуктов животного и растительного происхождения. Особое внимание уделено факторам, влияющим на скорость порчи, включая условия хранения, температурный режим, микробную контаминацию и технологические особенности производства. Обобщены результаты исследований, посвящённых применению традиционных лабораторных методов и современных экспресс-технологий контроля качества, включая биосенсоры и индикаторные системы. Подчёркнута роль комплексной оценки качества как основы профилактики пищевых отравлений и обеспечения санитарно-эпидемиологического благополучия населения.
subject: Articles
  topic: section
subject:
  topic: keywords
  value: скоропортящиеся пищевые продукты, качество продукции, пищевая безопасность, микробиологические показатели, органолептическая оценка, физико-химические методы, условия хранения, санитарный контроль, гигиена питания.
creator: Азимов К.К.
rights: Copyright (c) 2026
date: 2026-02-09
publication date: 2026-02-09
starting page: 47
ending page: 54

Охрана труда в сельском хозяйстве. Влияние токсичных химических веществ на здоровье человека и профилактические меры
type: item
description: В обзорной статье рассматриваются вопросы охраны труда в сельском хозяйстве с акцентом на влияние токсичных химических веществ на здоровье человека и меры их профилактики. Проанализированы современные данные о воздействии пестицидов, агрохимикатов, удобрений и других химических соединений, широко применяемых в сельскохозяйственном производстве, на организм работников. Особое внимание уделено острым и хроническим эффектам химического воздействия, включая поражения дыхательной системы, кожи, нервной и эндокринной систем, а также риски профессиональных отравлений. Обобщены результаты эпидемиологических и экспериментальных исследований, свидетельствующие о высокой уязвимости сельскохозяйственных работников к химическим факторам производственной среды. Рассмотрены основные профилактические меры, включая санитарно-гигиенические требования, использование средств индивидуальной защиты, медицинский контроль и обучение работников. Подчёркнута ключевая роль системы охраны труда в снижении профессиональных рисков и сохранении здоровья работников сельского хозяйства.
subject: Articles
  topic: section
subject:
  topic: keywords
  value: охрана труда, сельское хозяйство, токсичные химические вещества, пестициды, профессиональные риски, здоровье работников, химические факторы, профилактические меры, производственная гигиена, профессиональные заболевания.
creator: Азимов К.К.
rights: Copyright (c) 2026
date: 2026-02-09
publication date: 2026-02-09
starting page: 39
ending page: 46

Постменопаузальный генитоуринарный синдром: клинико-патогенетические аспекты, диагностика и современные подходы к терапии
type: item
description: Постменопаузальный генитоуринарный синдром является одной из наиболее распространённых проблем здоровья женщин старшей возрастной группы и характеризуется комплексом морфологических, функциональных, клинических изменений урогенитального тракта, обусловленных длительным дефицитом эстрогенов. Несмотря на высокую распространённость, данное состояние остаётся недодиагностированным и недостаточно леченным. Целью исследования является анализ современных представлений о патогенезе, клинических проявлениях, диагностике и терапии постменопаузального генитоуринарного синдрома на основе данных международных научных публикаций. В работе обобщены результаты исследований, посвящённых морфологическим изменениям урогенитального тракта, влиянию гипоэстрогении и возможностям патогенетической терапии. Особое внимание уделено междисциплинарному подходу к диагностике и лечению.
subject: Articles
  topic: section
subject: генитоуринарный синдром, постменопауза, гипоэстрогения, вульвовагинальная атрофия, гормональная терапия, урогенитальные нарушения.
  topic: keywords
creator: Зарипова Дилноза Яшиновна
creator: Буриева Чарос Барот кизи
rights: Copyright (c) 2026
date: 2026-02-07
publication date: 2026-02-07
starting page: 35
ending page: 38

Myocardial infarction: etiology, clinical characteristics, myocardial biomarkers, pathophysiological and anatomical features based on clinical research and statistical analysis
type: item
description: Myocardial infarction (MI) is one of the most severe and clinically significant manifestations of ischemic heart disease and remains a leading cause of morbidity and mortality worldwide. This condition is fundamentally characterized by irreversible necrosis of cardiomyocytes resulting from prolonged ischemia, most commonly associated with acute obstruction of coronary blood flow. Over recent decades, large-scale epidemiological and clinical studies have provided deeper insights into the multifactorial etiology of myocardial infarction, the evolution of its clinical features, and the complexity of its pathophysiological mechanisms. This article presents a comprehensive scientific review based on statistical data, theoretical models, and findings from major clinical investigations related to myocardial infarction. The analysis encompasses etiological factors, global and regional incidence rates, disease prevalence and mortality trends, as well as characteristic structural and functional alterations of the myocardium. Myocardial biomarkers are biochemical substances released into the bloodstream following myocardial tissue injury and play a crucial role in the early detection and diagnosis of myocardial infarction. The principal myocardial biomarkers include troponin (I and T), creatine kinase MB fraction (CK-MB), myoglobin, and lactate dehydrogenase (LDH). Troponin demonstrates high sensitivity and specificity and is regarded as the gold standard for confirming myocardial infarction. The primary clinical significance of CK-MB lies in the detection of reinfarction. Myoglobin is the earliest marker to rise, although it lacks cardiac specificity. LDH is a late-rising biomarker and is currently used in limited clinical settings. Particular attention is given to the pathophysiological cascade linking coronary artery pathology with myocardial injury, as well as to cellular and tissue-level anatomical changes. By synthesizing data from peer-reviewed studies, meta-analyses, a…
subject: Articles
  topic: section
subject: Myocardial infarction, etiology, epidemiology, pathophysiology, coronary disease, ischemia, necrosis, statistics, mortality, anatomy, clinical research, cardiovascular, myocardial biomarkers.
  topic: keywords
creator: Ibrohimova Husnora Martavali kizi
rights: Copyright (c) 2026
date: 2026-02-05
publication date: 2026-02-05
starting page: 24
ending page: 34

Miokard infarktning ilk va kechki bosqichlaridagi gistologik o‘zgarishlar. Hujayra darajasidagi aniqlovchi omillar
type: item
description: Maqolada miokard infarktning ilk va kechki bosqichlaridagi gistologik o‘zgarishlarni hujayra darajasidagi aniqlovchi omillar doirasida turli davrlar darajalari bo‘yicha ko‘rib chiqilgan va nazariy - analitik tahlillar o‘tkazilgan. Yurak mushagida sodir bo‘ladigan gistologik hamda morfologik o‘zgarishlar jarayonlari bosqichma-bosqich tahlil qilingan va o‘tkazilgan analitik tahlillarning davolash jaraenidagi ahamiyati ko‘rsatib o‘tilgan. Miokard infarktning ilk va kechki bosqichlaridagi gistologik o‘zgarishlarni hujayra darajasidagi aniqlovchi omillar ustida olib borilgan ilmiy tadqiqotlar yurak-qon tomir kasalliklariga qarshi kurashdagi yangi vositalarni ishlab chiqish va amaliyotga tadbiq qilizga zamin yaratadi.
subject: Articles
  topic: section
subject: Miokard infarkti, gistologik o‘zgarishlar, hujayra, yurak mushagi, qon-tomir kasalliklari, yurak to‘qimalari
  topic: keywords
creator: Ubaydullayev G‘olibjon
rights: Copyright (c) 2026
date: 2026-02-05
publication date: 2026-02-05
starting page: 17
ending page: 23

Clinical effectiveness of modern endodontic diagnostic methods: a theoretical and evidence-based analysis
type: item
description: Accurate diagnosis is a cornerstone of successful endodontic treatment, directly influencing therapeutic decision-making and long-term clinical outcomes. Over the past two decades, endodontic diagnostics have undergone significant transformation with the introduction of advanced imaging technologies, digital tools, and biologically oriented testing methods. These innovations have improved clinicians’ ability to detect pulpal and periapical pathologies at earlier stages, differentiate between reversible and irreversible conditions, and evaluate complex root canal anatomy with greater precision. This article provides a comprehensive theoretical and evidence-based analysis of the clinical effectiveness of modern endodontic diagnostic methods. The study synthesizes data derived from peer-reviewed scientific articles, systematic reviews, and doctoral dissertations indexed in major biomedical databases. Emphasis is placed on comparing traditional diagnostic approaches with contemporary techniques such as cone-beam computed tomography, digital radiography, electronic pulp testing, laser Doppler flowmetry, and thermal vitality tests. Statistical findings reported in the literature demonstrate that modern diagnostic modalities significantly increase diagnostic accuracy, sensitivity, and specificity, thereby reducing the incidence of misdiagnosis and unnecessary treatment. Furthermore, these methods enhance clinician confidence, improve treatment planning, and contribute to higher success rates in endodontic therapy. The article concludes that the integration of advanced diagnostic technologies into routine clinical practice represents a fundamental shift toward precision-based endodontics and establishes a new standard of care.
subject: Articles
  topic: section
subject: Endodontics, diagnosis, imaging, CBCT, pulp vitality, digital radiography, accuracy, sensitivity, specificity, prognosis, innovation, dentistry
  topic: keywords
creator: Sobirova Dilnoza Akbarjon kizi
rights: Copyright (c) 2026
date: 2026-02-03
publication date: 2026-02-03
starting page: 11
ending page: 17

Conservative and surgical treatment approaches for periodontitis with emphasis on apical root resection: an evidence-based theoretical and statistical analysis
type: item
description: Periodontitis remains one of the most prevalent chronic inflammatory diseases of the oral cavity, frequently leading to progressive destruction of periodontal tissues and potential tooth loss if inadequately managed. The complexity of its pathogenesis necessitates a comprehensive therapeutic strategy that integrates both conservative and surgical modalities. Among surgical interventions, apical root resection (apicoectomy) occupies a pivotal role in the management of persistent periapical pathology unresponsive to conventional endodontic therapy. This article presents a theoretically grounded and statistically informed analysis of conservative and surgical approaches to periodontitis treatment, with particular emphasis on the indications, biological rationale, and clinical outcomes of apical root resection. Data synthesized from peer-reviewed articles, clinical trials, and doctoral dissertations demonstrate that combined treatment strategies significantly improve periodontal stability, reduce inflammatory burden, and enhance long-term tooth survival. Conservative measures, including mechanical debridement and antimicrobial control, serve as the foundation of therapy, whereas surgical techniques address anatomical and pathological complexities inaccessible through nonsurgical means. Reported success rates for apical root resection range between 70% and 95%, depending on case selection and operator expertise. The integration of evidence-based protocols, advanced diagnostic tools, and refined surgical techniques contributes to predictable outcomes. This review underscores the necessity of individualized treatment planning and multidisciplinary collaboration to optimize therapeutic success in periodontitis management.
subject: Articles
  topic: section
subject:
  topic: keywords
  value: Periodontitis, conservative therapy, surgical treatment, apicoectomy, root-end resection, periodontal inflammation, bone regeneration, endodontic surgery, clinical outcomes, periapical lesions, evidence-based dentistry, tooth preservation
creator: Sobirova Dilnoza Akbarjon kizi
rights: Copyright (c) 2026
date: 2026-02-03
publication date: 2026-02-03
starting page: 4
ending page: 10

STENORKARDIYA KASALLIGI, UNING DIAGNOSTIKASI HAMDA TERAPIYASI
type: item
description: Ushbu maqolada yurak ishemik kasalligining keng tarqalgan turlaridan biri bo‘lgan stenokardiya haqida so‘z boradi. Stenokardiya kasalligining kelib chiqish sabablari, diagnostikasi, klinik belgilari va xavf omillari tahlil qilinadi. Shuningdek, kasallikni aniqlash uchun zamonaviy diagnostika usullari, jumladan, elektrokardiografiya (EKG), yurakni stress testi, koronar angiografiya, Magnit-rezonans tomografiya (MRT) va shu kabi qator tekshiruvlar tavsiflanadi hamda davolash usullari yoritib beriladi. Maqola stenokardiyani chuqurroq tushunish, uning oldini olish va samarali davolash usullarini o‘rganishga yordam beradi.
subject: Articles
  topic: section
subject:
  topic: keywords
  value: Stenokardiya, stabil stenokardiya, nostabil stenokardiya, rinzmetal stenokardiya, mikrovaskulyar stenokardiya, koronar arteriyalar, miokard ishemiyasi, EKG, MRT,beta-blokatorlar, nitratlar, Antiplatelet vositalar, statinlar, angioplastika, stentlash, aorto-koronar shuntlash.
creator: Muqumjonov Omadullo O‘ktamjon o‘g‘li
creator: Jumayev Nosirbek Abdullayevich
rights: Copyright (c) 2026
date: 2026-01-31
publication date: 2026-01-31
starting page: 44
ending page: 47

PARKINSON KASALLIGI ETIOLOGIYASI, PATOGENEZI HAMDA DAVOLASH USULLARI
type: item
description: Ushbu maqolada Parkinson kasalligining etiologiyasi, patogenezi va klinik belgilari bilan birga, zamonaviy davolash usullari yoritilgan. Jumladan, dori vositalari, neyroximik terapiya, jarrohlik amaliyotlari (chuqur miya stimulyatsiyasi) va gen terapiya yo‘nalishlari tahlil qilingan. Tadqiqotda kasallikning rivojlanishini sekinlashtirishga va bemorlarning hayot sifatini oshirishga qaratilgan yo‘nalishlar bayon etilgan.
subject: Articles
  topic: section
subject: Parkinson kasalligi, dopamin, levodopa, chuqur miya stimulatsiyasi, gen terapiya, nevrodegeneratsiya.
  topic: keywords
creator: Muqumjonov Omadullo O‘ktamjon o‘g‘li
creator: Jumayev Nosirbek Abdullayevich
rights: Copyright (c) 2026
date: 2026-01-31
publication date: 2026-01-31
starting page: 40
ending page: 43

Ambulatoriya sharoitida homilador ayollarda temir tanqisligi anemiyasini davolashni takomillashtirish
type: item
description: Homilador ayollarda temir tanqisligi kamqonligi eng keng tarqalgan ekstragenital patologiyalardan biri bo'lib qolmoqda, ayniqsa ambulatoriya sharoitida. Bu holat homiladorlik, tug'ish va tug'ruqdan keyingi davrga salbiy ta'sir qiladi va ona va homila uchun asoratlar xavfini oshiradi. Ushbu maqolada ambulatoriya sharoitida homilador ayollarda temir tanqisligi kamqonligini davolashni takomillashtirishning joriy yondashuvlari ko'rib chiqiladi. Erta tashxis qo'yish, individual ravishda temir qo'shimchalarini kiritish, davolash samaradorligini baholash va bemorga rioya qilishga alohida e'tibor beriladi. Temir o'z ichiga olgan preparatlarning og'iz shakllarini qo'llash natijalari, shuningdek, homiladorlik davri va kamqonlik darajasini hisobga olgan holda kombinatsiyalangan terapiya sxemalari tahlil qilindi. Homilador ayollarda temir tanqisligi kamqonligi eng keng tarqalgan ekstragenital patologiyalardan biri bo'lib qolmoqda, ayniqsa ambulatoriya sharoitida. Bu holat homiladorlik, tug'ish va tug'ruqdan keyingi davrga salbiy ta'sir qiladi va ona va homila uchun asoratlar xavfini oshiradi. Ushbu maqolada ambulatoriya sharoitida homilador ayollarda temir tanqisligi kamqonligini davolashni takomillashtirishning joriy yondashuvlari ko'rib chiqiladi. Erta tashxis qo'yish, individual ravishda temir qo'shimchalarini kiritish, davolash samaradorligini baholash va bemorga rioya qilishga alohida e'tibor beriladi. Temir o'z ichiga olgan preparatlarning og'iz shakllarini qo'llash natijalari, shuningdek, homiladorlik davri va kamqonlik darajasini hisobga olgan holda kombinatsiyalangan terapiya sxemalari tahlil qilindi.
subject: Articles
  topic: section
subject: Anemiya sindromi, temir tanqisligi,homiladorlik davri, ambulatoriya monitoringi,gemoglobinni tuzatish, ona salomatligi, perinatal xavflar.
  topic: keywords
creator: Jabbarova Yulduz Qosimovna.
creator: Abdullayeva Dilnura
rights: Copyright (c) 2026
date: 2026-01-31
publication date: 2026-01-31
starting page: 35
ending page: 39

Temir tanqisligi anemiyasidan aziyat chekuvchi xomilador ayollarda preeklampsiya profilaktikasining samaradorligi
type: item
description: Temir tanqisligi anemiyasi homilador ayollarda eng keng tarqalgan ekstragenital patologiyalardan biri bo'lib, preeklampsi rivojlanish xavfini sezilarli darajada oshiradi. Temir tanqisligi to'qimalarning nafas olishini buzadi, endotelial disfunktsiyani oshiradi va gipoksiyani oshiradi, bu esa homiladorlik asoratlarining rivojlanishiga yordam beradi. O'z navbatida, preeklampsi onalar va perinatal kasalliklar va o'limning asosiy sababi bo'lib qolmoqda. Ushbu tadqiqotning maqsadi temir tanqisligi anemiyasi bo'lgan homilador ayollarda preeklampsi uchun profilaktika choralarining samaradorligini baholashdir. Maqolada profilaktika bo‘yicha zamonaviy yondashuvlar, jumladan, kamqonlikni o‘z vaqtida tuzatish, temir preparatlarini qo‘llash, ratsional ovqatlanish, homilador ayollarning ahvolini har tomonlama dinamik kuzatish tahlil etilgan.
subject: Articles
  topic: section
subject: temir tanqisligi anemiyasi, homilador ayollar, preeklampsiya, profilaktika, gemoglobin, ona-homila salomatligi.
  topic: keywords
creator: Ismoilova Shoira Tolkunovna.
creator: Erkinova Nilufar
rights: Copyright (c) 2026
date: 2026-01-31
publication date: 2026-01-31
starting page: 30
ending page: 34

Особенности ранней диагностики и факторы риска осложнения муковисцидоза у детей раннего возраста
type: item
description: Муковисцидоз (МВ) является одним из наиболее распространённых наследственных заболеваний с аутосомно-рецессивным типом наследования, характеризующимся поражением экзокринных желёз и развитием тяжёлых респираторных и гастроинтестинальных осложнений уже в раннем детском возрасте. Несмотря на внедрение неонатального скрининга, своевременная диагностика и прогнозирование осложнённого течения заболевания остаются актуальной проблемой педиатрии. В статье рассмотрены особенности ранней диагностики муковисцидоза у детей раннего возраста, а также проанализированы основные факторы риска развития осложнений. Полученные результаты подчёркивают значимость комплексного клинико-лабораторного и генетического подхода для раннего выявления заболевания и оптимизации тактики ведения пациентов.
subject: Articles
  topic: section
subject: муковисцидоз, ранняя диагностика, дети раннего возраста, факторы риска, осложнения.
  topic: keywords
creator: Джураева К.Й.
rights: Copyright (c) 2026
date: 2026-01-20
publication date: 2026-01-20
starting page: 25
ending page: 29

Возможности ультразвукового исследования в выявлении смещения суставного диска при дисфункции височно-нижнечелюстного сустава
type: item
description: В статье представлены результаты клинического исследования, посвящённого оценке диагностических возможностей ультразвукового исследования (УЗИ) при выявлении смещения суставного диска у пациентов с дисфункцией височно-нижнечелюстного сустава (ВНЧС). Исследование проведено в 2022–2024 годах на базе стоматологических клиник Республики Узбекистан и включало 92 пациента с клиническими признаками дисфункции ВНЧС. УЗИ применялось для оценки положения суставного диска в покое и при функциональных пробах. Полученные данные сопоставлялись с клинической картиной и результатами других методов диагностики. Установлено, что ультразвуковое исследование обладает высокой информативностью при выявлении переднего смещения суставного диска и может рассматриваться как доступный и безопасный метод первичной диагностики дисфункции ВНЧС.
subject: Articles
  topic: section
subject: височно-нижнечелюстной сустав; ультразвуковое исследование; смещение суставного диска; дисфункция ВНЧС; диагностика.
  topic: keywords
creator: Рахимова Зарина Дамировна
rights: Copyright (c) 2026
date: 2026-01-13
publication date: 2026-01-13
starting page: 21
ending page: 24

CHRONIC GANGRENOUS PULPITIS: ETIOLOGY, CLINICOPATHOLOGICAL CHARACTERISTICS AND PATHOGENESIS
type: item
description: Chronic gangrenous pulpitis represents an advanced degenerative-inflammatory condition of the dental pulp characterized by extensive tissue necrosis and putrefactive changes. From a theoretical and scientific perspective, this pathology develops as a consequence of prolonged microbial invasion, compromised pulpal microcirculation, and progressive hypoxia within the confined pulp chamber. The present article provides a comprehensive theoretical analysis of chronic gangrenous pulpitis based exclusively on anatomical, histological, hydrodynamic, and statistical data derived from established scientific literature. Clinical case descriptions and patient-based observations are deliberately excluded to ensure a purely conceptual and evidence-based approach. Particular attention is given to the etiological factors that disrupt pulpal homeostasis, the molecular and cellular mechanisms underlying pulpal gangrene, and the anatomical peculiarities that predispose the pulp to irreversible degeneration. Furthermore, the article synthesizes findings from peer-reviewed articles, dissertations, and classical endodontic theories to elucidate the structural and functional alterations observed in chronic gangrenous pulpitis. By integrating hydrodynamic concepts of pulpal pressure, vascular collapse, and toxin diffusion, this review aims to clarify the pathogenesis of pulpal gangrene and its implications for dental hard tissues and periapical structures. The study contributes to a deeper theoretical understanding of chronic gangrenous pulpitis and provides a structured scientific basis for future experimental and translational research in endodontic pathology.
subject: Articles
  topic: section
subject: chronic pulpitis, pulp gangrene, dental pulp, necrosis, microcirculation, hypoxia, inflammation, anaerobic bacteria, dentin permeability, toxins, histopathology, endodontics.
  topic: keywords
creator: Ergashev Bekzod Jaloliddin ugli
rights: Copyright (c) 2026
date: 2026-01-05
publication date: 2026-01-05
starting page: 15
ending page: 20

Maktab yoshdagi bolalarda karies rivojlanishining asosiy xavf omillari: etiologiyasi, klinikasi va profilaktik chora-tadbirlari
type: item
description: Ushbu ilmiy-nazariy maqolada maktab yoshidagi bolalarda tish kariesi rivojlanishining asosiy xavf omillari, etiologik mexanizmlari, klinik ko‘rinishlari va profilaktik yondashuvlari kompleks tarzda yoritilgan. Kariesning shakllanish jarayoni tish to‘qimalarining anatomik tuzilishi, emalning mineral tarkibi hamda og‘iz bo‘shlig‘i muhitining biologik xususiyatlari bilan chambarchas bog‘liq ekani asoslab beriladi. Maqolada ovqatlanish ratsioni xususiyatlari, gigiyenik odatlar, ftor balansining buzilishi, travmatik ta’sirlar va ijtimoiy omillarning karies rivojlanishiga ta’siri ilmiy manbalar asosida tahlil qilingan. Shuningdek, maktab yoshida uchraydigan karies turlari, ularning klinik kechishi va asoratlari nazariy jihatdan bayon etilgan. Profilaktik chora-tadbirlar individual, guruhli va jamoaviy yondashuvlar asosida tizimlashtirilgan. Statistik tahlillar asosida kariesning global tarqalish tendensiyalari va xavf omillarining nisbiy ulushi ko‘rsatib berilgan. Maqola stomatologiya sohasida ilmiy-tadqiqot va profilaktik dasturlarni takomillashtirish uchun nazariy asos bo‘lib xizmat qiladi.
subject: Articles
  topic: section
subject: karies, maktab yoshi, etiologiya, klinika, profilaktika, emal, dentin, ftor, travma, gigiyena, statistika, xavf omillari
  topic: keywords
creator: Ergashev Bekzod
creator: Parpiyeva Odinaxon Raxmanovna
rights: Copyright (c) 2026
date: 2026-01-05
publication date: 2026-01-05
starting page: 9
ending page: 14

THE ROLE OF MITOCHONDRIAL DYSFUNCTION IN HUMAN DISEASES
type: item
description: Mitochondria are essential organelles responsible for cellular energy production, regulation of apoptosis, calcium homeostasis, and reactive oxygen species (ROS) balance. Dysfunction of mitochondria has emerged as a central pathological mechanism in numerous human diseases, ranging from neurodegenerative and cardiovascular disorders to metabolic and age-related conditions. Recent advances in molecular biology and genetics have uncovered the intricate relationship between mitochondrial DNA (mtDNA) mutations, oxidative stress, and impaired bioenergetics in disease development. This paper discusses the biological basis of mitochondrial dysfunction, its systemic implications for human health, and the therapeutic strategies aimed at restoring mitochondrial integrity and function. Understanding mitochondrial biology not only reveals insights into the fundamental processes of life but also provides new avenues for the diagnosis and treatment of complex diseases.
subject: Articles
  topic: section
subject: mitochondria, dysfunction, oxidative stress, human diseases, bioenergetics, mtDNA, apoptosis, metabolism
  topic: keywords
creator: Toshpulatova Durdona Sharifbekovna
rights: Copyright (c) 2026
date: 2026-01-05
publication date: 2026-01-05
starting page: 4
ending page: 8

TEACHING MEDICAL STUDENTS ABOUT MORPHOLOGICAL CHANGES IN DIFFERENT PARENCHYMATOUS ORGANS
type: item
description: Understanding inflammation-induced morphological changes in parenchymatous organs is essential for effective medical education, as these alterations represent the structural foundation of disease and clinical dysfunction. This article emphasizes teaching medical students the key morphological and anatomo-physiological changes associated with inflammatory processes, using the upper respiratory organs as an illustrative and clinically relevant model. Inflammation leads to epithelial damage, stromal remodeling, vascular alterations, and glandular dysfunction, all of which directly impair organ function. The article highlights the educational value of integrating classical histopathology with modern approaches such as digital microscopy and structure–function correlation. By linking morphological patterns to functional consequences, this teaching framework enhances diagnostic reasoning, supports clinical decision-making, and aligns with current trends in competency-based medical education. Morphology is thus presented as a dynamic, integrative discipline that bridges basic pathology and clinical practice.
subject: Articles
  topic: section
subject: inflammation, morphology, parenchyma, respiratory, pathology, education
  topic: keywords
creator: Yusupova Gulnara Karimovna
rights: Copyright (c) 2026
date: 2025-12-30
publication date: 2025-12-30
starting page: 96
ending page: 101

IMPROVING MEDICAL STUDENTS' CRITICAL THINKING IN PATIENT DIAGNOSIS
type: item
description: Critical thinking is a core competency for accurate patient diagnosis and safe clinical decision-making. Traditional lecture-based medical education often fails to sufficiently develop diagnostic reasoning skills required in real clinical environments. This study evaluated the effectiveness of a structured educational intervention integrating instructional videos, authentic patient cases, and repeated Objective Structured Clinical Examinations (OSCEs) in enhancing critical thinking among medical students. A total of 212 undergraduate medical students were divided into an intervention group and a control group and followed longitudinally through 2025. Descriptive statistical analysis demonstrated meaningful improvements in diagnostic accuracy, clinical reasoning scores, and OSCE performance among students exposed to the intervention. These findings support the integration of multimodal, case-based, and assessment-driven teaching strategies in modern medical curricula.
subject: Articles
  topic: section
subject: criticalthinking, diagnosis, medicaleducation, OSCE, videos, simulation, assessment
  topic: keywords
creator: Toshmatov Farxodjon Rustamovich
rights: Copyright (c) 2025
date: 2025-12-29
publication date: 2025-12-29
starting page: 91
ending page: 95

Embrional rivojlanish davrlari va uning umumiy tavsifi: urug‘lanish, zigota, maydalanish, blastula, gastrulyatsiya, gistogenez, organogenez
type: item
description: Mazkur maqolada embrional rivojlanishning asosiy bosqichlari va ularning biologik mohiyati yoritilgan. Jumladan, urug‘lanish jarayoni natijasida zigotaning hosil bo‘lishi, undan keyingi maydalanish bosqichi, blastula shakllanishi, gastrulyatsiya jarayonida embrion qatlamlarining vujudga kelishi, shuningdek gistogenez va organogenez bosqichlarida to‘qima va organlarning rivojlanish mexanizmlari ilmiy asosda tahlil qilingan. Embrional rivojlanish bosqichlarining o‘zaro bog‘liqligi, hujayralar differensiyatsiyasi va morfogenetik jarayonlarning ahamiyati ochib berilgan. Maqola biologiya, tibbiyot va pedagogika yo‘nalishlarida tahsil olayotgan talabalar hamda ushbu sohada ilmiy tadqiqot olib borayotgan mutaxassislar uchun nazariy manba bo‘lib xizmat qiladi.
subject: Articles
  topic: section
subject: embrional rivojlanish, urug‘lanish, zigota, maydalanish, blastula, gastrulyatsiya, gistogenez, organogenez, hujayra differensiyatsiyasi, embrion qatlamlari
  topic: keywords
creator: Tursunova Oygul Ahmadjonovna
rights: Copyright (c) 2025
date: 2025-12-25
publication date: 2025-12-25
starting page: 88
ending page: 90

EARLY IDENTIFICATION OF OVARIAN FUNCTIONAL DECLINE AND CONTEMPORARY APPROACHES TO CLINICAL MANAGEMENT
type: item
description: Premature impairment of ovarian function represents a critical gynecological and endocrinological challenge with profound reproductive and systemic consequences. Declining ovarian reserve before the age of natural menopause disrupts fertility potential, endocrine balance, and long-term metabolic health. Timely recognition of ovarian functional decline is essential to prevent irreversible infertility, skeletal demineralization, and cardiovascular morbidity. This comparative observational study evaluated early diagnostic indicators and management perspectives of ovarian insufficiency by analyzing clinical manifestations, hormonal parameters, and ultrasonographic markers. A total of 56 women were enrolled, including 28 patients with ovarian insufficiency and 28 age-matched healthy controls examined at the Fergana District Medical Association. Significant alterations were observed in gonadotropin concentrations, estradiol levels, anti-Müllerian hormone values, ovarian volume, and antral follicle count among affected patients.
subject: Articles
  topic: section
subject: ovarian insufficiency, ovarian reserve, early diagnosis, hormonal biomarkers, reproductive endocrinology, fertility preservation, hormone therapy
  topic: keywords
creator: Dadajonova Mashhura Akhmadjon kizi
creator: Alieva Zarnigor Valijon kizi
rights: Copyright (c) 2025
date: 2025-12-21
publication date: 2025-12-21
starting page: 83
ending page: 87

GAYMORID: KELIB CHIQISH SABABLARI, BELGILARI VA DAVOLASH USULLARI
type: item
description: Gaymorid (maksillyar sinusit) – yuqori jag‘ bo‘shlig‘i shilliq qavatining yallig‘lanishi bo‘lib, ko‘pincha o‘tkir respirator infeksiyalar, allergik omillar, anatomik o‘zgarishlar yoki mikroorganizmlar faollashuvi natijasida yuzaga keladi. Mazkur maqolada gaymoridning etiologiyasi, klinik belgilari, tasnifi, diagnostika usullari, konservativ va jarrohlik davolashning zamonaviy yondashuvlari ilmiy manbalar asosida yoritilgan.
subject: Articles
  topic: section
creator: Abdumutalibova Mohigul
rights: Copyright (c) 2025
date: 2025-12-21
publication date: 2025-12-21
starting page: 81
ending page: 82

ХАВФ ОМИЛЛАРИНИ ТАРҚАЛИШИНИ ЮРАК-ҚОН ТОМИР КАСАЛЛИКЛАРИ УЧУН ТАХЛИЛ ҚИЛИШ
type: item
description: "Ёш аёллар ва уларнинг саломатлиги" маълумотлар базасини яратиш ва бирламчи бўғинда ташкил этилган тиббий ва руҳий кузатиш амалга оширишни ўз ичига олади ўрта ёшдаги аёлларда жисмоний меҳнатнинг ўзига хос жиҳатлари, атеросклероз фонида юрак-қон томир касаллиги ва гипертония тарқалиши частотаси боғлиқлигини кўрсатади. Турмуш тарзига киритилган кичик ўзгаришлар ҳам юракнинг қаришини секинлаштириши мумкин. Соғлом турмуш тарзини бошлаш жуда кеч эмас. Юрак-қон томир касаллиги белгилари пайдо бўлганидан сўнг, хавф омиллари касалликнинг ривожланишига ҳисса қўшади ва прогнозни ёмонлаштиради, шунинг учун уларни тузатиш даволаш усулларининг ажралмас қисми бўлиши керак.
subject: Articles
  topic: section
subject: юрак ишемик касаллиги, артериал гипертензия, аёллар, хавф омиллари, турмуш тарзи.
  topic: keywords
creator: Рахматова Дилбар Баҳриддиновна
rights: Copyright (c) 2025
date: 2025-12-21
publication date: 2025-12-21
starting page: 76
ending page: 80

Kuyish jarohatlarida AST va ALT ko‘rsatkichlarining o‘zgarishi: RSHTYoIM BF kuzatuvlari asosida
type: item
description: Kuyish jarohatlari global sog‘liqni saqlash tizimida muhim o‘rin egallab, har yili 180 mingdan ortiq o‘lim holatlariga sabab bo‘ladi (WHO, 2022). Kuyishdan so‘ng organizmda yuzaga keladigan gipermetabolik javob yallig‘lanish mediatorlarining ortishi, to‘qimalar perfuziyasining buzilishi va ko‘plab ichki organlar, xususan jigar faoliyatining izdan chiqishi bilan xarakterlanadi (Jeschke, 2009). Gepatositlar darajasida sodir bo‘ladigan apoptoz va nekroz jarayonlari jigar fermentlari – aspartat aminotransferaza (AST) hamda alanin aminotransferaza (ALT) – ning erta oshishiga olib keladi (Nielson et al., 2017). Tadqiqotning maqsadi — 2023–2025 yillar davomida RSHTYoIM BF kuyish bo‘limida davolangan 89 bemorda AST va ALT ko‘rsatkichlarining o‘zgarishini tavsiflash.
subject: Articles
  topic: section
creator: Barnoyev S.Sh.
rights: Copyright (c) 2025
date: 2025-12-17
publication date: 2025-12-17
starting page: 74
ending page: 75

HAMSHIRALIK XIZMATIDA EMPATIYA VA KOMMUNIKATIV KO'NIKMALARNING AHAMIYATI
type: item
description: Ushbu maqolada hamshiralik faoliyatida empatiya va kommunikativ ko'nikmalarning o'rni, ularning bemorlarni davolash jarayoniga ta'siri hamda zamonaviy tibbiy xizmat ko'rsatish sifatini oshirishdagi ahamiyati tahlil qilingan. Maqolada empatiyaning psixologik mexanizmlari, hamshira-bemor muloqotining turli jihatlari va professional kommunikatsiyaning tibbiy natijalar bilan bog'liqligi ko'rib chiqilgan.
subject: Articles
  topic: section
subject: hamshiralik xizmati, empatiya, kommunikativ ko'nikmalar, bemor-hamshira muloqoti, tibbiy xizmat sifati, professional kompetensiya
  topic: keywords
creator: Imomova Zulfiya Zuxriddinovna
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 70
ending page: 73

Jamiyatda daltanizm: muammolar va yechimlar
type: item
description: Daltanizm — ranglarni ajrata olmaslik bilan kechuvchi ko‘rish nuqsoni bo‘lib, uning keng tarqalganligi jamiyat hayotining turli jabhalarida muammolarni yuzaga keltiradi. Ushbu maqolada daltanizmning biologik asoslari, uning ijtimoiy hayotga ta’siri, ta’lim va kasb tanlashdagi cheklovlari, shuningdek, texnologik va pedagogik yechimlar tahlil qilinadi. Tadqiqot davomida mavjud ilmiy manbalar o‘rganilib, rang ko‘rish nuqsoniga ega shaxslarga moslashtirilgan dizayn, ko‘makchi texnologiyalar va jamiyatdagi inkluziv yondashuvlarning ahamiyati yoritildi. Olingan xulosalar daltanizm muammosini kamaytirish va rang sezgirligi past bo‘lgan shaxslar uchun qulay muhit yaratishning muhimligini ko‘rsatadi. [1,7; 3,22]
subject: Articles
  topic: section
subject: Daltanizm, rang ko‘rish nuqsoni, protanopiya, deuteranopiya, ijtimoiy moslashuv, inkluziv dizayn, Ishihara testi, ko‘makchi texnologiyalar.
  topic: keywords
creator: Dumayeva Muqaddamoy
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 61
ending page: 69

Новые стратегии борьбы с антибиотикорезистентностью: современное состояние и перспективные направления
type: item
description: Антибиотикорезистентность (АР) остаётся одной из наиболее значимых глобальных угроз здравоохранению. Рост распространённости мультирезистентных и панрезистентных бактерий требует поиска инновационных терапевтических и профилактических решений. В обзоре представлены современные стратегии противодействия АР, включая быстрые методы диагностики, разработку новых антибактериальных молекул, фаготерапию, применение антимикробных пептидов, CRISPR-технологий, наноматериалов, а также мероприятия по рациональному использованию антибиотиков. Рассмотрены их преимущества, ограничения и перспективы клинического внедрения.
subject: Articles
  topic: section
subject: антибиотикорезистентность, бактериофаги, антимикробные пептиды, CRISPR, stewardship, быстрые методы диагностики.
  topic: keywords
creator: Герасимова Алёна Андреевна
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 57
ending page: 60

ГАСТРИТ: ЭТИОЛОГИЯ, ПАТОГЕНЕЗ, КЛИНИЧЕСКИЕ ПРОЯВЛЕНИЯ И СОВРЕМЕННЫЕ ПОДХОДЫ К ЛЕЧЕНИЮ
type: item
description: ГАСТРИТ: ЭТИОЛОГИЯ, ПАТОГЕНЕЗ, КЛИНИЧЕСКИЕ ПРОЯВЛЕНИЯ И СОВРЕМЕННЫЕ ПОДХОДЫ К ЛЕЧЕНИЮ
subject: Articles
  topic: section
subject: : образ жизни, вредные привычки, стресс, ибупрофен, слизистая оболочка.
  topic: keywords
creator: Ўктамова Рухсора Уткиржон кизи
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 54
ending page: 56

METABOLIK SINDROM: PATOGENEZ, KLINIK AHAMIYATI VA PROFILAKTIK YONDASHUVLAR
type: item
description: Metabolik sindrom (MS) — bu abdominal semizlik, insulinrezistentlik, arterial gipertenziya, dislipidemiya va uglevod almashinuvi buzilishlari bilan tavsiflanadigan murakkab patofiziologik holatlar majmuasidir. MS so‘nggi yillarda dunyo miqyosida ham, O‘zbekiston aholisi orasida ham keskin oshib bormoqda. Bu holatning xavfi shundaki, u yurak-qon tomir kasalliklari, 2-turdagi qandli diabet, ateroskleroz va miokard infarkti rivojlanishi uchun kuchli mustaqil xavf omili hisoblanadi.
subject: Articles
  topic: section
creator: Mavlonov Namoz Halimovich
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 51
ending page: 53

GASTRIT: ETIOLOGIYASI, PATOGENEZI, KLINIK KO‘RINISHLARI VA DAVOLASHNING ZAMONAVIY YONDASHUVLARI
type: item
description: Gastrit — bu me’da shilliq qavatining yallig‘lanishi bilan kechadigan kasallik bo‘lib, u o‘tkir va surunkali shakllarda namoyon bo‘ladi. Surunkali gastrit dunyo aholisining qariyb 50–60%ida uchraydi va ko‘pincha Helicobacter pylori infeksiyasi, nosog‘lom ovqatlanish, stress, zararli odatlar hamda dori vositalarining (NSAID) uzoq muddat qabul qilinishi bilan bog‘liq. Yoshlarning hayot tarzi o‘zgarishi, fast-food iste’moli, stressning ortishi gastrit uchrash chastotasining ko‘payishiga olib kelmoqda.
subject: Articles
  topic: section
subject: hayot tarzi, zararli odatlar, stress, ibuprofen, shilliq qavat.
  topic: keywords
creator: Mavlonov Namoz Halimovich
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 48
ending page: 50

МЕТАБОЛИЧЕСКИЙ СИНДРОМ: ПАТОГЕНЕЗ, КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ И ПРОФИЛАКТИЧЕСКИЕ ПОДХОДЫ
type: item
description: Метаболический синдром (МС) — это комплекс патологических состояний, характеризующийся абдоминальным ожирением, инсулинорезистентностью, артериальной гипертензией, дислипидемией и нарушениями углеводного обмена. В последние годы наблюдается резкий рост распространённости МС как во всем мире, так и среди населения Узбекистана. Опасность данного состояния заключается в том, что оно является мощным независимым фактором риска развития сердечно-сосудистых заболеваний, сахарного диабета 2-го типа, атеросклероза и инфаркта миокарда. В формировании МС ведущую роль играют генетическая предрасположенность, неправильное питание, недостаточная физическая активность, стрессовые воздействия и гормональные нарушения. Ранняя диагностика и комплексная профилактика имеют важное значение для снижения бремени сердечно-сосудистых заболеваний.
subject: Articles
  topic: section
subject: абдоминальное ожирение, сердечно-сосудистые заболевания, атеросклероз, сахарный диабет.
  topic: keywords
creator: Мавлонов Намоз Халимович
rights: Copyright (c) 2025
date: 2025-12-11
publication date: 2025-12-11
starting page: 44
ending page: 47